I have a defense mechanism that is nearly always effective. It's simple, straight-forward and would probably work with anyone. Anyone who has a conscience anyway. Here's how it goes:
Brandon begins to show signs of wrestling me down to tickle me, lick my toes or some equally horrible violent act. I, seeing this as a potential threat to my safety and well-being, immediately begin saying "OW OW OW OW OW!!!!!"
As stated before, this almost always works to at least deter him until I have a chance to gather my physical defenses.
I'm just saying, if you have anyone in your life who tries to cause you terrible-ness give this defense mechanism a try. Yell out a painful word/scream before they actually get a chance to make contact. It may buy you some time to come up with a better defense mechanism.